Germs is a game that combines quick thinking with even quicker reflexesas players manipulate scads of colorful, killer pathogens in order toneutralize a biological threat and save humanity. The gameplay is quite simple, relying at its core on the "pick pieces upand place them on the gameboard" model used in several games such asMacPipes. In Germs, the player picks up germ sprites from a "culturedish" and arranges them on the gameboard in patterns of the same colorto make them disappear.